The subject of this dissertation is the development of printed electronic devices through inkjet technology. A key activity of the dissertation is the study of different types of inks, both commercial and experimental, through which the proposed devices will be fabricated. Basic electrical, thermal, and general physical properties will be extensively studied to determine the behavior of inks in multilayer printed structures. The aim of this action is to optimize the fabrication of predefined geometry patterns through a specialized inkjet printer. Furthermore, various devices of printed sensors (temperature, humidity, deformation, and chemical sensors) will be developed on various flexible substrates (paper, PET, Kapton etc.). Over the last decade, graphene has emerged as a very interesting material suitable for the manufacture of flexible electronics as a result of its electronic, optical, and thermal properties. Graphene can be used for various applications of more complex electronic devices such as semiconductor channels for high-speed transistors. This dissertation is focusing on the design, study and fabrication of a fully printed graphene-based field-effect transistor device. This is an innovative action as it includes the combination of materials-inks with different properties (conductors, insulators, semiconductors) as well as multilayer structures, which require precision patterning and insulation. The produced devices will be extensively characterized both in terms of their electrical behavior and in terms of their reliability. Additionally, an effort will be made to extract appropriate information from printed transistors such as creating a tool focused on materials used to build semiconductors that could be part of an existing commercial design package or a fully standalone software, which could correctly assess the response of the specific devices (Process / Physical Design Kit / PDK).